Gene description for RAB27A
Gene name RAB27A, member RAS oncogene family
Gene symbol RAB27A
Other names/aliases GS2
HsT18676
RAB27
RAM
Species Homo sapiens
 Experiment description of studies that identified RAB27A in Breast cancer cells

1
Experiment ID575
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBreast cancer cells
Sample nameBT549
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

2
Experiment ID576
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBreast cancer cells
Sample nameHS 578T
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

3
Experiment ID578
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleBreast cancer cells
Sample nameMDA-MB-231
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

4
Experiment ID2419
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35939247   
OrganismHomo sapiens
Experiment descriptionMetastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems
AuthorsKhan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.
Journal name Clin Exp Metastasis
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-231T
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

5
Experiment ID2420
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35939247   
OrganismHomo sapiens
Experiment descriptionMetastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems
AuthorsKhan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.
Journal name Clin Exp Metastasis
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-231T
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

6
Experiment ID2421
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35939247   
OrganismHomo sapiens
Experiment descriptionMetastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems
AuthorsKhan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.
Journal name Clin Exp Metastasis
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-435
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

7
Experiment ID2422
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35939247   
OrganismHomo sapiens
Experiment descriptionMetastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems
AuthorsKhan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.
Journal name Clin Exp Metastasis
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-435
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

8
Experiment ID2423
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35939247   
OrganismHomo sapiens
Experiment descriptionMetastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems
AuthorsKhan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.
Journal name Clin Exp Metastasis
Publication year2022
SampleBreast cancer cells
Sample nameT47D
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

9
Experiment ID2424
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35939247   
OrganismHomo sapiens
Experiment descriptionMetastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems
AuthorsKhan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.
Journal name Clin Exp Metastasis
Publication year2022
SampleBreast cancer cells
Sample nameMCF-7
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

10
Experiment ID2425
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35939247   
OrganismHomo sapiens
Experiment descriptionMetastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems
AuthorsKhan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.
Journal name Clin Exp Metastasis
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-453
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

11
Experiment ID2426
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35939247   
OrganismHomo sapiens
Experiment descriptionMetastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems
AuthorsKhan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.
Journal name Clin Exp Metastasis
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-436
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

12
Experiment ID2427
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35939247   
OrganismHomo sapiens
Experiment descriptionMetastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems
AuthorsKhan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.
Journal name Clin Exp Metastasis
Publication year2022
SampleBreast cancer cells
Sample nameMDA-MB-468
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

13
Experiment ID2429
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Western blotting
PubMed ID 35939247   
OrganismHomo sapiens
Experiment descriptionMetastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems
AuthorsKhan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.
Journal name Clin Exp Metastasis
Publication year2022
SampleBreast cancer cells
Sample nameBT549
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
EV-TRACK -

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